出版社:化学工业出版社
年代:2011
定价:128.0
本书是由2010年7月在兰州召开的多肽中国国际会议优秀冷文精选而成。
Preface
The Eleventh Chinese Peptide Symposium (CPS-2010)
Acknowledgments
Cathay Award
Xiaoyu Hu Memorial Award
Chinese Peptide Symposium
Abbreviations
Session 1 Design of Peptides and Mimetics 1
Biomimetic Nanostructures Based on Enforced Folding and Assembly 3
Bing Gong
Agonist vs. Antagonist Behavior of Opioid Peptides Containing Novel
Tyrosine or Phenylalanine Analogues in Place of Tyr1 13
Grazyna Weltrowska, Irena Berezowska, Brian C. Wilkes, Carole Lemieux,
Nga N. Chung, Jinguo Ding, Yixin Lu, Peter W. Schiller,
Novel Non-Peptide Ghrelin Receptor Ligands Based on
3,4,5-Trisubstituted 1,2,4-Triazoles 20
Jean-Alain Fehrentz, Anne-Laure Blayo, Mathieu Bibian, Aline Moulin, Luc
Demange, Damien Boeglin, Céline M’Kadmi, Jean-Claude Galleyrand,
Didier Gagne, Vittorio Locatelli, Antonello Torsello, Daniel Perrissoud,
Jean Martinez,
Synthesis and Structure-Activity Relationship of Marinostatin,
An Ester-Linked Serine Protease Inhibitor 25
Misako Taichi, Toshimasa Yamazaki, Tadashi Teshima, Yuji Nishiuchi
Mitocryptides: A Novel Family of Neutrophil-Activating Peptides Derived
from Mitochondrial Proteins and Their Regulatory Mechanisms 30
Hidehito Mukai, Tetsuo Seki, Akiyoshi Fukamizu, Yoshiaki Kiso
Novel Opioid Peptide Derived Antagonists Containing 3-(2,6- Dimethyl-4-
Carbamoylphenyl)-Propanoic Acid (Dcp) in Place of Tyr1 33
Peter W. Schiller, Grazyna Weltrowska, Thi M.-D. Nguyen, Carole Lemieux,
Nga N. Chung, Tze Keong Lum, Yoon Wui Leow Augustine, Yixin Lu
Design, Synthesis and Evaluation of Antitumor Activity against
Human Cancer Cell Lines, Sansalvamide Analogues 39
Xiaoli Zhen, Yihua Yang, Junzhang Li, Xia Tian, Hua Zhang, Shouxin Liu
Session 2 Peptide Synthesis and Preparation 41
Regioselective Disulfide Bond Formation during SPS of Human Relaxin-3:
Evaluation of An Alternative Method for Removal of the S-Acm Groups via
Reaction with Silver Triflate and Subsequent Mild Aqueous
DMSO Oxidation 43
Feng Lin, John D. Wade
Synthetic Studies of Membrane Proteins: Subunit C of Human F1Fo-ATP
Synthase and Voltage Sensor Only Protein (78-222) 47
Saburo Aimoto, Ken’ichiro Nakamura, Takeshi Sato, Toru Kawakami,
Toshiaki Hara
One-Pot Synthesis of Rigid Cyclic N-Methyl-γ-Peptides 54
Zhongzhu Chen, Liangchun Li, Menglan Lv, Jin Zhu and Jingen Deng
Tbfmoc Methioine: Its Synthesis and Application for the Solid Phase
Synthesis of Ubiquitin Analogues and Product Purification 58
Naifeng Hu, Zhi Jin, Pu Wang
Intein-Mediated Biosynthesis of Bracelet Cyclotide 63
Xinya Hemu, Lin Cai, Clarence T. T. Wong, James P. Tam
Convergent and Atom-Economic Synthesis of Phosphinopeptides 67
Fanhua Meng, Jiaxi Xu
One-Step Oxidative Folding of A Novel Cystine-Knot Cyclotide
Under Denaturation Conditions 69
Clarence T. T. Wong, Misako Taichi, Hideki Nishio, Yuji Nishiuchi,
James P. Tam
Synthesis of Angiotensin I-Converting Enzyme Inhibitory Peptides and
Their Self-Assembling Microstructure Characterization 72
Dawei Li, Yan Ding, Gang Cao, Ruijie Zhang, Jin Ren, Chuanguang Qin
Fast Automated Synthesis of An Antimicrobial Peptide Analog
Using UV-Monitoring on the Tribute? 77
German E. Fuentes, Christina A. Chantell, Hirendra Patel, Mahendra
Menakuru
Synthesis of Cyclic Peptides by Alknye-Azide Click Chemistry Cyclization 81
Liangyou Wang, Dongdong Lu, Mingxing Lu
Thioester Preparation through O-S Acyl Shift under Acidic Condition 83
Khee Dong Eom, Young Soon Shin, James P. Tam
A Novel Strategy for Total Solid-Phase Synthesis of
Kahalalide A Derivatives 86
Tingting Wei, Jin Ren, Xiaoya Shang, Gang Cao, Chuanguang Qin
Session 3 Methodologies in Peptide Research 91
Protein Synthesis Using Novel Ligation Partners 93
Wen Hou, Renliang Yang, Fupeng Li, Xiaohong Zhang, Chuanfa Liu
Expanding Role of Mass Spectrometry for Characterization of Proteins 97
Pui-kin So, Zhongping Yao
Effect of pH on the Self-Assembly of Surfactant-Like Peptides 102
Shuyi Han, Jing Wang, Hai Xu
Conformational Isomers in N-Methylzygosporamide Cyclic Pentapeptides 110
Yihua Yang, Shirui Gao, Xianrui Yuan, Shouxin Liu, Wei Meng, Guodi Qi
Interaction between Amyloid-β-Peptide (1-40) and Its Aggregation
Inhibitors Studied by Circular Dichroism 112
Qing Zeng
Disulfide Bond Formation Directed by Watson-Crick Base Pairing 116
Fupeng Li, Xiaohong Zhang, Wen Hou, Chuanfa Liu
Interfacial Adsorption of Novel Lipopeptide Surfactant C14K3: A Combined
Study of Spectroscopic Ellipsometry and Neutron Reflection 120
Donghui Jia, Kai Tao, Jiqian Wang, Xiubo Zhao, Hai Xu, John R. P.
Webster, Jian R. Lu
Session 4 Peptide Therapeutics and Application 135
Peptide-Based Nanoparticles for Cancer Therapy and Imaging 137
Yuanpei Li, Kai Xiao, Juntao Luo, Wenwu Xiao, Joyce Lee,
Lorenzo Berti, Kit S. Lam
Involvement of Na+,K+-ATPase in Leukemia Cell Apoptosis
by Modulating Sensitivity 145
Wu Yin, Wei Cheng, Wei Chen, Dan Cao, Su Feng, Xinyin Chen, Jin Zhao,
Yilin Shi, Zichun Hua
Short Constrained Dipeptide Mimic Oligomers as Uncharged Cell
Penetrating Compounds 157
Lubomir L. Vezenkov, Christophe André, David Paramelle, Marie Maynadier,
Jean-Francois Hernandez, Marcel Garcia, Monique Calmès, Gilles Subra,
Ettore Benedetti, Jean Martinez, Muriel Amblard
Synthesis and Biological Properties of Peptide-siRNA Conjugates 161
Zhenjun Yang, Xiaofeng Wang, Yang Liu, Yue Chen, Feilin Nie, Lihe Zhang
FGF-P Facilitates Cell Proliferation Following Ionizing Radiation 167
Yeping Tian, Shanmin Yang, Mei Zhang, Yongbing Cao, Bingrong Zhang,
Lei Zhang, Liangjie Yin, Kunzhong Zhang, Steven G. Stwarts, Bruce M.
Fentona, Paul Okunieff, Lurong Zhang
Synthesis, Evaluation and Molecular Modeling Study of L-2-amino-7/8-
Bromoalkanoic Acid Derivatives as Histone Deacetylase Inhibitors 172
Dawei Huang, Xiaohui Li , Zhilong Xiu, Norikazu Nishino
Thirteen-Membered Cyclic Tetrapeptides as Histone Deacetylase Inhibitors 177
Hongfang Chi, Yasuhiko Otsuka, Tamaki Kato, Norikazu Nishino,
Akihiro Ito, Minoru Yoshida
Antimicrobial Peptide May be Desirable Candidate for the Treatment of
Multidrug-Resistant Cancer & Bacteria: A Simple Introduction to the
Therapeutic Effects of A Novel Antimicrobial Peptide Polybia-MPI 182
Kairong Wang, Bangzhi Zhang, Jiexi Yan, Wei Zhang, Ru Chen,
Jingjing Song, Rui Wang
Remodeling of Cyclic Tetrapeptides Framework of Chlamydocin as
Histone Deacetylase Inhibitors 188
Jiani Li, Xiaohui Li, Yasuhiko Otsuka, Tamaki Kato, Norikazu Nishino,
Akihiro Ito, Minoru Yoshida
Identification of Novel HLA-A*0201-Restricted Cytotoxic T
lymphocyte Epitopes from PLAC1 in Breast Cancer 192
Wei Liu, Mingxia Zhai, Chao Dai, Yuanming Qi, Yanfeng Gao
Session 5 Bioactive Peptides and Pharmacology 197
In Vitro Characterization for the Effects of Insect Kinins on Mouse
Distal Colonic Motility 199
Longfei Yang, Yang Xiao, Yun Huang, Guoning Ma, Zhiyuan Cong,
Shouliang Dong
Evaluation of the Bioequivalence of the 20 mg /10 ml Doses of Two
Injectable Preparations of Eptifibatide: A Randomized, Open-Label,
Two-Period Crossover Study in Healthy Adult Male Chinese Volunteers 204
Yanhui Gao, Baoqiu Li, Jun Sun
The Characteristics of Sleep-Wake States and Potential Neuronal
Targets for Neuropeptide S 210
Peng Zhao, Yufeng Shao, Min Zhang, Kun Fan, Rui Wang, Yiping Hou
Antibacterial Activity of Surfactant-Like Linear Amphipathic
Cationic Peptides 218
Jing Hu, Cui X. Chen, Sheng Z. Zhang, Hai Xu, Jian R. Lu
Comparison of the Pharmacological Functions of the NPFF1
and NPFF2 Receptors Ligands 229
Quan Fang, Ning Li, Rui Wang
Preparation of Monomeric B27 Lys Destripeptide Insulin by
Intein Mediated Expression in E. Coli 236
Lujuan Li, Helong Hao, Yuanhao Qiao, Ting Chen
Endomorphins Prevent Cardiac Oxidative Damage Induced
by Cadmium Chloride in Rats 241
Pin Gong, Fuxin Chen, Rui Wang
Study on Anticancer Mechanism of Cyclic Tetrapeptide HDACIs 246
Shimiao Wang, Xiaohui Li, Zhilong Xiu, Norikazu Nishino 246
Biological Roles of Hemokinin-1: A Novel Member of
the Tachykinin Family 251
Ziqing Kong, Wenle Yang, Caiyun Fu, Youli Zhao, Yan Tao, Rui Wang
Author Index 257
Subject Index 260
The 11th Chinese International Peptide Symposium (CPS-2010), hosted by Lanzhou University, was held in Lanzhou, China, July 5-8, 2010. More than 300 participants, from 12 countries and districts as well as represents from 30 or so related companies attended this symposium. Thus, it was gratifying to see that this meeting retained both its international flavor and participants loyalty at a time when there are a great many symposia held each year on similar subjects. The goal of this symposium was to provide a forum for exchange of ideas, review of the progress in the field of peptide research, encourage the cooperation between the international and Chinese scientific communities. We believe that this goal had been achieved.
The scientific program, thanks to the insights and efforts of the program committee, was extraordinary rich, diverse and exciting. It was comprised of 14 sessions with 22 plenary lectures, 37 invited lectures and 116 poster presentations, concerning bioactive peptides, peptide immunology, structure and conformation of peptides and proteins, molecular diversity and peptide libraries, synthetic methods, de novo design and synthesis of proteins and peptides, ligand-receptor interactions, the chemistry-biology-interface, self-assembling peptides and challenging problems in peptides.
Dr. John D. Wade and Dr. Yanmei Li were the recipients of ‘Cathay Award’ sponsored by H. H. Liu Education Foundation, offering their seminal contributions to peptide science and the Chinese International Peptide Symposium. Dr. Saburo Aimoto and Dr. Luhua Lai were the recipients of ‘Xiaoyu Hu Memorial Award’ sponsored by Hainan Zhonghe (Group) Co. Ltd, offering their great contributions in peptide science, peptide application and Chinese International Peptide Symposium. Especially, it should be mentioned that ‘Xiaoyu Hu Memorial Award’ was first set up at the 11th CPS to commemorate Professor Xiaoyu Hu for his great contribution to the development of peptide science and peptide application in China. Four young outstanding scientists were selected by the International Program Committee to receive the Young Peptide Scientist Award , which was sponsored by Hainan Zhonghe (Group) Co. Ltd.
The enthusiastic cooperation and prominent contributions were gratifying and the active response of the invited speakers contributed to the success of the symposium. The presentations were of excellent caliber and represented the most current and significant aspects of peptide science.
I would like to acknowledge academicians of chinese academy of sciences, Professor Youshang Zhang and Professor Yundong Wu for their kindness in supporting and serving as the chairman of the awarding committee for the ‘Cathay Award’ and ‘Xiaoyu Hu Memorial Award’ respectively. The success of the 11th CPS was largely due to the dedication, enthusiasm and hard work of the local organizing committee, who for the most part consisted of volunteers. As Symposium Chair, I am appreciated for their contributions very much.
书籍详细信息 | |||
书名 | 多肽药 : 理学、生物学和化学站内查询相似图书 | ||
9787122107886 如需购买下载《多肽药 : 理学、生物学和化学》pdf扫描版电子书或查询更多相关信息,请直接复制isbn,搜索即可全网搜索该ISBN | |||
出版地 | 北京 | 出版单位 | 化学工业出版社 |
版次 | 1版 | 印次 | 1 |
定价(元) | 128.0 | 语种 | 英文 |
尺寸 | 26 × 19 | 装帧 | 精装 |
页数 | 印数 |
多肽药 : 理学、生物学和化学是化学工业出版社于2011.5出版的中图分类号为 TQ464.7-53 的主题关于 多肽-药物-国际学术会议-文集-英文 的书籍。