药物化学进展

1信号转导与转录激活因子3（STAT3）抑制剂及其抗肿瘤研究进展1

Progress in the Research of STAT3 Inhibitors as Anticancer Agents

余文颖李洋孔令义

2选择性EGFR T790M抑制剂的研究进展17

Recent Advance on the Discovery of T790M Mutantselective EGFR Inhibitors

徐石林徐田锋丁克3FLT

3ITD及其抑制剂的研究进展38

Advances in FLT3 Internal Tandem Duplications Mutation and Inhibitors of FLT3ITD

钟杭蔡婷赵临襄

4组蛋白去甲基化酶及其抑制剂的研究进展57

Progress in the Research of Histone Demethylases and Their Inhibitors

郑一超刘宏民

5 组蛋白去乙酰化酶抑制剂研究进展77

Progress in Histone Deacetylase Inhibitors

安娜高明邓卫平

6NAD+依赖的组蛋白去乙酰化酶(Sirtuin)激活剂与抑制剂的研究进展107

Progress in NAD+dependent Sirtuins Activators and Inhibitors

王磊方浩

7靶向IKKβ激酶抑制剂的研究进展120

Progress in Targeting IKKβ Kinase Inhibitors

褚红喜黄婧婕孙昊鹏尤启冬

8缺氧诱导因子(HIF)介导肿瘤耐药及其相关药物的研究进展131

The Research Development of Hypoxiamediated Drug Resistance and Drug Candidates

陈亚琼彭晖

9天然萜类化合物逆转肿瘤和细菌多药耐药的研究进展159

Progress in the Research of Natural Terpenes as Reversal Agents of Multidrug Resistance in Cancer and Bacteria

张恒源徐进宜

10抗菌肽设计的研究进展179

Recent Studies on Designing Antimicrobial Peptides

张伟谢俊秋张邦治王锐

11治疗糖尿病的新策略——SGLT2抑制剂202

A Novel Strategy for Diabetes TreatmentSGLT2 Inhibitors

王学堃钱海黄文龙

12GPR40 和GPR120调控剂的研究进展225

Progress in GPR40 and GPR120 Modulators

雷显涛温小安孙宏斌

13抗阿尔茨海默病药物研究进展255

Progresses of the Development of antiAlzheimer Drugs

房雷苟少华

14载体转运系统介导的脑靶向药物研究进展281

Progress in Carriermediated Brain Targeting Drugs

吴勇李晓岑海俐

15与重大疾病相关的糖类药物的研究进展303

Progress in the Research of Carbohydratebased Drugs Associated with Major Diseases

王晓丽田光宗汪学彬尹健

16一氧化氮供体偶氮二醇盐的O2保护策略及其应用研究进展321

Research Progress in O2protection and Application of Nitric Oxide Donor Diazeniumdiolates

黄张建赖宜生彭司勋张奕华

《药物化学进展（10）》是由彭司勋院士主持，国内药物化学领域及相关学科教授、院士编写的系列读物，从2002年开始，迄今已出版10卷。该书是收录了一系列药物研发领域具有前瞻性和指导性的文章，有助于开阔试验，拓展思路。