多肽化学与生物学

多肽化学与生物学

刘克良, 程卯生, 孟庆斌, 主编

出版社:化学工业出版社

年代:2013

定价:168.0

书籍简介:

本书为英文版图书,是Proceedings of the 12th Chinese International Peptide Symposium中精选的优秀论文。本书内容涵盖多肽研究的各个方向,包括其化学、药物及生物学,重点阐述了其研究进展。

书籍目录:

Preface

The 12th Chinese International Peptide Symposium (CPS-2012)

Acknowledgements

Cathay Award

Xiaoyu Hu Memorial Award

Chinese Peptide Symposium

Abbreviations

Session 1 Innovative Methodology of Peptide/ Protein Synthesis

N-to-C Sequential Ligation Method for Protein Total Synthesis

Renliang Yang, Wen Hou, Xiaohong Zhang, Chuan-Fa Liu

Total Solid-phase Combinatorial Synthesis of Biologically Active

N-Decanoyl Depsipeptide Derivatives from Natural Products

Chuanguang Qin, Qiuyu Wang, Lin Li, Tingting Wei, Jin Ren

The Synthesis of Alkyne-human Relaxin-2 for Labeling with Different

Azido Molecules by Click Chemistry

Feng Lin, Linda Chan, Laszlo Otvos Jr. and John D. Wade

4-Methoxybenzyloxymethyl Group as a Thiol Protecting Group for

Cysteine to Prevent Racemization in Fmoc Chemistry

Hajime Hibino, Yuji Nishiuchi

Bio-Inspired Thrombomodulin Conjugate Engineering via Recombinant

and Bio-Orthogonal Conjugation Technique

Hailong Zhang, Jacob Weingart, Rui Jiang and Xue-Long Sun

Acid-catalyzed N-S Acyl Shift for Preparing Peptide Thioesters Using

Fmoc Chemistry

Yibo Qiu, Clarence T. T. Wong and James P. Tam

Solid-Phase Synthesis of Side-Chain-Protected Peptides via a Linker-

Modified Resin

Zhi-Ping Huang, Ming Zhang

Development of Peptide Modification Methods to Widely Expand

Peptide Structural Diversity and Its Applications

Xinjun Zhang, Wentao Zhang

Session 2 Peptide/Protein Material Sciences

Synthetic and Self-assembly Studies of a Series of Gemini Peptides

Changhai Cao, Meiwen Cao, Daohong Xia, Hai Xu

Fabrication of Globular Protein/Polysaccharide-PAA Aggregates

Naipu He, Sikai Huang, Xi Du, Weigang Zhao,

Shengfang Lu, Xiaoqian Han

High-efficiency Cellular Penetrable Superparamagnetic Nanoparticle

Complexation with Tat Peptide Conjugates

Chenhong Wang, Lei Qiao, Keliang Liu

Biological Activities of Integrin-binding Peptides Derived from

Laminins on Alginate and Chitosan Matrices

Kazuhiro Sato, Yuji Yamada, Kentaro Hozumi, and Motoyoshi Nomizu

Session 3 Technological Advances in Peptide Purification and Analysis

Intein-mediated Expression of Cyclic Sunflower Trypsin Inhibitor in E. coli

Shunyi He, Ting Chen, Wei Zhang, Rong Feng, Youshang Zhang

Perfection of the Universal Method for Screening Affinity Adsorbents

Used for Phosphorylated Peptide Isolation Utilizing Gold Colloids

Qinqin Wei, Wei Wang, Bicui Wang, Jun Wang, Zhi Yuan

Session 4 Peptide drug discovery and design

New Paradigms for Drug Discovery and Development: Design of

Multivalent Ligands for the Treatment of Disease

Victor J. Hruby, Takashi Yamamoto, Padma Nair, Minying Cai,

Josef Vagner, Jatinder Josan, Robert J. Gillies, Liping Xu,

David Morse, Peg Davis, Shou-Wu Ma, Tally Largent-Milnes,

Josephine Lai, Eva Varga, Todd Vanderah, Frank Porreca

Edible Biologics: Orally Active Peptide Bradykinin B1 Receptor

Antagonists for Inflammatory Pain Treatment

James P. Tam, Clarence T. T. Wong

Small-sized BACE1 Inhibitors: In-silico Design and Synthesis

Yoshio Hamada, Harichandra D. Tagad, Yoshiaki Kiso

Design of Novel Relaxin-3 Agonist Analogues as Potential

Neurological Regulators

Fazel Shabanpoor, M. Akhter Hossain, Feng Lin, Ross A.D. Bathgate,

Andrew Gundlach, John D. Wade

2-Oxoamides Based on Amino Acids and Dipeptides as Selective

Phospholipase A2 Inhibitors Presenting Anti-inflammatory Activity

George Kokotos

N-Methylation of Cyclized Melanotropine Peptides: A New

Perspective of Drug Discovery for Melanocortin System

Minying Cai, Jennifer Bao, Morgan R. Zingsheim, Johannes G. Beck,

Florian Opperer, Lucas Doedens, Horst Kessler Victor J. Hruby

Design, Synthesis, and Pharmacological Evaluation of Novel

Tasiamide B Derivatives: Selective Inhibitors of BACE1

Jian Liu, SimingYang, Wei Zhang, Ning Ding, Yingxia Li

Autophagy Inhibition Promotes HDACI-induced Apoptosis in

MCF-7 Breast Cancer Cells

Shimiao Wang, Xiaohui Li, Zhilong Xiu

The Mechanism of Amyloid Protein Aggregation and the Design

of Fibrillization Inhibitors

Meng-Rong Ma and Yan-Mei Li

Anti-HIV-1 Small Molecule-Peptide Conjugates for Studying Target

Binding of Small Molecule Fusion Inhibitors

Chao Wang, Weiguo Shi, Lifeng Cai, Kun Wang, Keliang Liu

A Peptide-based Fluorescence Probe for Trypsin Activity and

a Potent Inhibitor

Junchen Wu, Tian He, Carsten Schmuck

Development of RGD-MEK1/2 Inhibitor Conjugates for Targeted

Delivery in Melanoma Treatment

Xiaoxiao Li, Cao Wang, Shanyun Gao, Jianjun Hou, Zhangjun Yang,

Lihe Zhang, Zili Chen, Yun Wu

Chemical Synthesis of Irisin and Detection in Human Blood

Aydar Sabirov, Xiang-Qun Chen, Rong-Ming Lyu, Qing Tian,

Siok L. Dun Nae J. Dun, and Jaw-Kang Chang

……

内容摘要:

《多肽化学与生物学》是一本英文版的药学化学专业著作,它阐述了包括创新的合成方法、结构和多肽和蛋白质的构象,和蛋白质材料科学、技术进步在肽纯化和分析、肽药物发现和设计、生物活性肽,配体受体相互作用,化学生物学界面和具有挑战性的问题在多肽。

书籍规格:

书籍详细信息
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出版地北京出版单位化学工业出版社
版次1版印次1
定价(元)168.0语种英文
尺寸24 × 17装帧平装
页数印数

书籍信息归属:

多肽化学与生物学是化学工业出版社于2013.5出版的中图分类号为 Q516-53 的主题关于 多肽-化学-文集-英文 ,多肽-生物学-文集-英文 的书籍。