分子生物学

Chapter 1 Historical Review of Molecular Biology

1.1 Definition of Molecular Biology

1.2 Brief History of Molecular Biology

1.3 Basic Content of Molecular Biology

1.4 Role of Molecular Biology in Medical Science

Chapter 2 Transmission of Genetic Information

2.1 DNA Replication

2.2 Transcription

2.3 Translation

Chapter 3 Gene Regulation

3.1 Gene Regulation in Prokaryotes

3.2 Gene Regulation in Eukaryotes

3.3 Noncoding RNA and RNA Interference

3.4 Epigenetic Regulation of Gene Expression

3.5 Gene Regulatory Network

Chapter 4 DNA Damage and Repair

4.1 Factors Causing DNA Damage

4.2 Types of DNA Damage

4.3 DNA Repair Mechanisms

4.4 DNA Damage Caused Effects

Chapter 5 Protein Modification， Trafficking and Degradation

5.1 Folding of Nascent Polypeptide Chains

5.2 Assembly of Protein Subunits

5.3 Posttranslational Modifications of Proteins

5.4 Transport and Localization of Proteins

5.5 Degradation of Cellular Proteins

5.6 Clinical Significance of Protein Modification， Trafficking and Degradation

Chapter 6 Molecular Cloning and Genetic Engineering

6.1 Cloning Enzymes

6.2 Cloning Vectors

6.3 Principle and Procedures of Molecular Cloning

6.4 Genetic Engineering

Chapter 7 Gene Characterization and Functional Analysis

7.1 Nucleic Acid Molecular Hybridization

7.2 Polymerase Chain Reaction

7.3 Nucleic Acid Sequencing

Chapter 8 Omics and System Biology

8.1 Genomics

8.2 Transcriptomics

8.3 Proteomics

8.4 Metabolomics

Chapter 9 Gene Transfer and Gene Targeting

9.1 Gene Recombination

9.2 Gene Transfer and Transgenic

9.3 Gene Targeting by Homologous Recombination

9.4 Transgenic and Its Application

Chapter 10 Molecular Biology of Cancer

10.1 Cell Cycle and Apoptosis

10.2 Oncogenes and Tumor Suppressor Genes

10.3 Molecular Basis of Cancer Development

《分子生物学/医学教育政策系列教材》系统论述细胞成分的物理、化学的性质和变化以及这些性质和变化与生命现象的关系，如遗传信息的传递，基因的结构、复制、转录、翻译、表达调控和表达产物的生理功能，以及细胞信号的转导等。《分子生物学/医学教育政策系列教材》主要面向在我国接受医学教育的海外留学生和接受双语教学的本科生。