疼痛的分子机理
出版社：高等教育出版社
年代：2006
定价：84.8
书籍简介:
本书是以最新研究进展为基础的教材。它在介绍疼痛研究的最新发现中阐明疼痛的基本分子机理，注重阐述如何运用疼痛模型研究神经科学问题和神经科学研究的新成果在疼痛研究中的应用；与经典的以传导路径为基础讲述疼痛理论的论著显著不同，该书力图按照相关领域的最新进展，建立起以分子、突触和系统为理论基础的研究方法。该书每章均由在有关领域有突出贡献的专家撰写，并经2-3名同行专家审阅，保证了它的科学性与可读性。该书可供生理学、解剖学、医学、护理学等专业的高年级大学生、研究生、科研人员以及临床疼痛科的医生使用。
书籍目录:
Major Contributors
Preface
The Guide to Use This Book
Part Ⅰ Genes，Neurons and Neurotransmission
Chapter 1 Genes and Neurons
Chapter 2 Synapses：Coupling of Presynaptic Voltage-gated Ca2+ Channels to Vesicular Release of Neurotransmitter
Chapter 3 Synaptic Vesicle Cycle at Nerve Terminals
Part Ⅱ Glutamate，Excitatory Transmission and Pain
Chapter 4 Postsynaptic Excitatory Transmission
Chapter 5 Kainate Receptors
Chapter 6 Excitatory Amino Acid Neurotransmitter Regulation
Chapter 7 Spinal Glutamate Receptors
Chapter 8 Glutamate Kainate Receptor in Pain Transmission and Modulation
Part Ⅲ Neuropeptides，ATP，Retrograde Messengers and OpiOids
Chapter 9 Neuropeptides
Chapter 10 ATPandItsReceptorsinPain
Chapter 11 Opioid Receptors
Chapter 12 Retrograde Messengers
Part Ⅳ Inhibitory Transmission and Plasticity
Chapter 13 Inhibitory Transmission
Chapter 14 Plastic@of Inhibition；GABA／glycine Systems
Part Ⅴ Postsynaptic Signaling and Gene Regulation
Chapter 15 Protein Kinases and Phosphatases
Chapter 16 Activity-dependent Gene Regulation： How Do SynapsesTalktotheNucleusand Fine-tune Neuronal Outputs
Chapter 17 Second Messenger Pathways in Pain
Chapter 18 Genetic Approaches for the Study of Pain
Part Ⅵ Peripheral Nocieeptor，Amygdala and Fear
Chapter 19 Peripheral Nociceptors
Chapter 20 Amygdala-Pain Processing and Pain Modulation
Chapter 21 Fear Learning
Part Ⅶ Spinal Plasticity，Reorganization and Chronic Pain
Chapter 22 Silent Glutamatergic Synapses and Long-term Facilitation in Spinal Dorsal Horn Neurons
Chapter 24 Spinal Microglia in Neuropathic Pain
Plasticity
Part Ⅷ Cortical Plasticity，Reorganization and Amputation
Chapter 25 ACC Plasticity
Chapter 26 Reorganization of the Sensorimotor System after Injury
Part Ⅸ Endogenous Analgesia and Other Form of Analgesia
Chapter 27 Endogenous Biphasic Modulation
Chapter 28 Paradoxical Analgesic and Hyperalgesic Efrects of Stress
Chapter 29 Acupuncture Analgesia
Chapter 30 Mechanisms of Opioid Tolerance
Part Ⅹ Models for Studying Pain and Searching for Pain Killers
Chapter 31 Models in Pain Research
Chapter 32 Models for Studying Pain and Searching for Pain Killers in Vitro Electrophysiological Studies ofPain
Chapter 33 Whole-cell Patch-clamp Recording in Vivo
Chapter 34 Basic Mechanisms of ClinicaUy Used Drugs
Selected References
Appendix Ⅰ Units in Pain Reaearch
Appendix Ⅱ Useful Wlebsites for the Study of Pain
Appendix Ⅲ List of Scientific Journals Publishing Studies in Pain
Appendix Ⅳ Fundamental and Innovative Contribution to Understanding of Basic Mechanism of Pain，Analgesia and Persistent Pain
内容摘要:
《疼痛的分子机理（英文版）》在介绍疼痛基本机理最新发现的同时讲授疼痛的基本理论，是以最新进展为基础的教材，并注重介绍应用疼痛模型研究神经科学问题和神经科学研究的新成果在疼痛研究中的应用。每章均由在领域内有突出贡献的专家撰写。该书可供生理学、解剖学、医学、护理学等专业的高年级大学生、研究生、科研人员以及临床疼痛科的医生使用。
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