激光快速成型骨支架进展

Preface

Chapter 1 Hydroxyapatite-Based Bone Scaffolds 1

1.1 Structural Design and Experimental Analysis of a Selective Laser

Sintering System with Nano-Hydroxyapatite Powder 2

1.2 Structure and Properties of Nano-Hydroxyapatite Scaffolds for Bone

Tissue Engineering with Selective Laser Sintering System 8

1.3 The Microstructure Evolution of Nano-Hydroxyapatite Powder Sintered for

Bone Tissue Engineering 21

1.4 Fabrication Optimization of Nano-Hydroxyapatite Artificial Bone

Scaffolds 32

1.5 Grain Growth Associates Mechanical Properties in Nano-Hydroxyapatite

Bone Scaffolds 43

1.6 Simulation of Dynamic Temperature Field during Selective Laser Sintering

of Ceramic Powder 51

1.7 Poly (L-lactide acid) Improves complete Nano-Hydroxyapatite

Bone Scaffolds through the Microstructure Rearrangement 59

1.8 Processing and Characterization of Laser Sintered Hydroxyapatite

Scaffold for Tissue Engineering 71

References 80

Chapter 2 Tricalcium Phosphate-Based Bone Scaffolds 91

2.1 Correlation between Properties and Microstructure of Laser Sintered

Porous β-Tricalcium Phosphate Bone Scaffolds 92

2.2 Analysis of Transient Temperature Distribution in Selective Laser

Sintering of β-Tricalcium Phosphate 106

2.3 Inhibition of Phase Transformation from β-to α-Tricalcium Phosphate

with Addition of Poly (L-lactic acid) in Selective Laser Sintering 113

2.4 Mechanical Properties Improvement of Tricalcium Phosphate Scaffold

with Poly (L-lactic acid) in Selective Laser Sintering 122

2.5 In vitro Bioactivity and Degradability of β-Tricalcium Phosphate Porous

Scaffolds Fabricated via Selective Laser Sintering 133

2.6 Characterization of Mechanical and Biological Properties of 3-D

Scaffolds Reinforced with Zinc Oxide for Bone Tissue Engineering 144

2.7 Nano-Hydroxyapatite Improves the Properties of β-tricalcium Phosphate

Bone Scaffolds 160

References 171

Chapter 3 Biodegradable Polymer-Based Bone Scaffolds 188

3.1 Fabrication of Porous Polyvinyl Alcohol Scaffold for Bone Tissue

Engineering via Selective Laser Sintering 188

3.2 Development of Complex Porous Polyvinyl Alcohol Scaffolds:

Microstructure， Mechanical and Biological Evaluations 198

3.3 Preparation of Complex Porous Scaffolds via Selective Laser Sintering

of Poly vinyl Alcohol/Calcium Silicate 206

3.4 Development of Composite Porous Scaffolds Based on Poly (Lactideco-

Glycolide) /Nano-Hydroxyapatite via Selective Laser Sintering 214

References 223

Chapter 4 Bioactive Glass-Based Bone Scaffolds 231

4.1 Fabrication and Characterization of Porous 45S5 Glass Scaffolds via

Direct Selective Laser Sintering 231

4.2 Enhancement Mechanisms of Graphene in Nano-58S Bioactive Glass

Scaffold: Mechanical and Biological Performance 239

References 254

Chapter 5 Other Bone Scaffolds 259

5.1 Fabrication and Characterization of Calcium Silicate Scaffolds for

Tissue Engineering 259

5.2 Graphene-Reinforced Mechanical Properties of Calcium Silicate

Scaffolds by Laser Sintering 270

5.3 Enhanced Sintering Ability of Biphasic Calcium Phosphate by Polymers

Used for Bone Scaffold Fabrication 280

5.4 Optimization of TCP/HAP Ratio for Better Properties of Calcium

Phosphate Scaffold via Selective Laser Sintering 294

5.5 Novel Forsterite Scaffolds for Bone Tissue Engineering: Selective Laser

Sintering Fabrication and Characterization 303

References 310

《Progress of Bone Scaffold by Laser Rapid Prototyping激光快速成型骨支架进展》系统介绍激光快速成型技术在人工骨支架制备中的研究现状，详细分析和归纳目前生物材料用于骨修复及再生的研究进展，全面总结骨支架材料的种类及特点，重点探讨不同骨支架材料的强度、韧性、生物相容性、降解性及其与组织细胞的相互作用规律，以期对骨组织缺损的修复与功能重建提供理论与技术指导。