2. However, according to a widely accepted theory, the universe began with a “Big Bang” that threw matter in all directions. begin with=start with：“以……开始”. 1) to begin with=to start with 以…为起点; 开始(做) 这两个词组都可以单独使用,表示“首先; 第一; 起 初; 最初”。 在句中作时间状语。 e.g. To begin/start with, I couldn’t like him at all. 起初, 我一句也没弄明白。